In-vivo dissolution studies have shown that -® delivers the target level of 20 mg per head per day of biotin over 120 days. Not only this, -® will also deliver the full daily requirement of copper, cobalt, iodine and selenium and useful contributions of manganese, zinc and vitamins A, D3 and E. Designed for grazing or forage fed dairy cows and heifers with a liveweight over 400 kg. Technology -® boluses are designed to lie in the reticulum and dissolve from a constant surface area thus providing a continuous and regular supply of nutrients to the animal. They dissolve completely, leaving the reticulum free of any bolus residue.